Your path to more personalized medication decisions

Your path to more personalized medication decisions

Pharmacogenomics (PGx) is a branch of precision medicine dedicated to understanding how genetic variants contribute to different responses to the same drug in different patients.

Pharmacogenomics (PGx) is a branch of precision medicine dedicated to understanding how genetic variants contribute to different responses to the same drug in different patients.

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One size does not fit all.

Drug effectiveness varies among individuals, with response rates for many medications ranging from 50% to 75%.¹ A significant factor contributing to this variability is the patient's genetic makeup.

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How PGx can help in patient care

How PGx can help in patient care

PGx testing offers healthcare teams valuable insights into how an individual's DNA may influence medication outcomes, enabling more informed decisions in patient care.

PGx testing offers healthcare teams valuable insights into how an individual's DNA may influence medication outcomes, enabling more informed decisions in patient care.

  • > 90% of patients have clinically actionable genetic variants.²

  • The FDA has an extensive list of pharmacogenomic biomarkers for drugs on the market today.³

  • Adverse drug reactions result in 1.5 million ER visits annually.⁴


PGx Screening Covers

PGx Screening Covers

Toxicity

Toxicity

The body absorbs more of a drug than is intended.

Lack of efficacy

Lack of efficacy

The body is unable to absorb the drug and the drug does not work as intended


Hypersensitivity

Hypersensitivity

A normal amount of the drug is absorbed, but the body reacts severely to the normal dose.


Common Medication Types Affected By Genetics

    • Anesthetics

    • Anticonvulsants

    • Central Nervous System Stimulants

    • Cholinesterase Inhibitors

    • Muscle Relaxants

    • S1P Receptor Modulators

    Neurology

    • Angiotensin II receptor blockers

    • Antiarrhythmics

    • Anticoagulants

    • Antihypertensives

    • Beta Blockers

    • Statins

    Cardiovascular

    • Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

    • Opioids

    • Anesthetics

    • Muscle Relaxants

    Pain Management

    • Antivirals

    • Antibiotics

    • Antimalarials

    • Antifungals

    Infectious Disease

    • Antidepressants

    • Antipsychotics

    • Benzodiazepines

    • Selective Serotonin Reuptake Inhibitors (SSRIs)

    Psychiatry

    • 5-HT3 Antagonists

    • Antineoplastic Agents

    • Estrogen Modulators

    • Kinase Inhibitors

    • Platinum Compounds

    • Purine Analogs

    • Pyrimidine Analogs

    Oncology

    • Proton-Pump Inhibitors

    Gastroenterology

    • Calcineurin Inhibitors

    • Immunosuppressants

    • Antiemetics

    • Antitussives

    • Sulfonylureas

    Other

    • Anesthetics

    • Anticonvulsants

    • Central Nervous System Stimulants

    • Cholinesterase Inhibitors

    • Muscle Relaxants

    • S1P Receptor Modulators

    Neurology

    • Angiotensin II receptor blockers

    • Antiarrhythmics

    • Anticoagulants

    • Antihypertensives

    • Beta Blockers

    • Statins

    Cardiovascular

    • Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

    • Opioids

    • Anesthetics

    • Muscle Relaxants

    Pain Management

    • Antivirals

    • Antibiotics

    • Antimalarials

    • Antifungals

    Infectious Disease

    • Antidepressants

    • Antipsychotics

    • Benzodiazepines

    • Selective Serotonin Reuptake Inhibitors (SSRIs)

    Psychiatry

    • 5-HT3 Antagonists

    • Antineoplastic Agents

    • Estrogen Modulators

    • Kinase Inhibitors

    • Platinum Compounds

    • Purine Analogs

    • Pyrimidine Analogs

    Oncology

    • Proton-Pump Inhibitors

    Gastroenterology

    • Calcineurin Inhibitors

    • Immunosuppressants

    • Antiemetics

    • Antitussives

    • Sulfonylureas

    Other

    • Anesthetics

    • Anticonvulsants

    • Central Nervous System Stimulants

    • Cholinesterase Inhibitors

    • Muscle Relaxants

    • S1P Receptor Modulators

    Neurology

    • Angiotensin II receptor blockers

    • Antiarrhythmics

    • Anticoagulants

    • Antihypertensives

    • Beta Blockers

    • Statins

    Cardiovascular

    • Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

    • Opioids

    • Anesthetics

    • Muscle Relaxants

    Pain Management

    • Antivirals

    • Antibiotics

    • Antimalarials

    • Antifungals

    Infectious Disease

    • Antidepressants

    • Antipsychotics

    • Benzodiazepines

    • Selective Serotonin Reuptake Inhibitors (SSRIs)

    Psychiatry

    • 5-HT3 Antagonists

    • Antineoplastic Agents

    • Estrogen Modulators

    • Kinase Inhibitors

    • Platinum Compounds

    • Purine Analogs

    • Pyrimidine Analogs

    Oncology

    • Proton-Pump Inhibitors

    Gastroenterology

    • Calcineurin Inhibitors

    • Immunosuppressants

    • Antiemetics

    • Antitussives

    • Sulfonylureas

    Other

    • Anesthetics

    • Anticonvulsants

    • Central Nervous System Stimulants

    • Cholinesterase Inhibitors

    • Muscle Relaxants

    • S1P Receptor Modulators

    Neurology

    • Angiotensin II receptor blockers

    • Antiarrhythmics

    • Anticoagulants

    • Antihypertensives

    • Beta Blockers

    • Statins

    Cardiovascular

    • Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

    • Opioids

    • Anesthetics

    • Muscle Relaxants

    Pain Management

    • Antivirals

    • Antibiotics

    • Antimalarials

    • Antifungals

    Infectious Disease

    • Antidepressants

    • Antipsychotics

    • Benzodiazepines

    • Selective Serotonin Reuptake Inhibitors (SSRIs)

    Psychiatry

    • 5-HT3 Antagonists

    • Antineoplastic Agents

    • Estrogen Modulators

    • Kinase Inhibitors

    • Platinum Compounds

    • Purine Analogs

    • Pyrimidine Analogs

    Oncology

    • Proton-Pump Inhibitors

    Gastroenterology

    • Calcineurin Inhibitors

    • Immunosuppressants

    • Antiemetics

    • Antitussives

    • Sulfonylureas

    Other

frequently asked questions

How do I order a test?

Tests can be ordered through the Provider Portal or by completing a paper Test Requisition Form.

How long does it take to receive the results?

It typically takes 3-4 weeks from the time a sample is mailed in to receiving the results in our secure provider portal. This timeframe reflects the complexity and precision of our process, as we partner with leading institution labs that adhere to clinical-grade quality control standards. We ensure that every step, from sample analysis to data interpretation, meets the highest level of accuracy and reliability.

Where do I access the results?

Healthcare providers can access their patients' results through the Provider Portal. In some instances, Strand offers direct integration with your EMR system. Contact us today to see if your EMR is supported for integration.

Is this test covered by insurance?

Proactive genetic screening is not covered by insurance, but it is typically eligible for HSA/FSA reimbursement. If you believe your patient may qualify for a diagnostic genetic test, please contact the Strand support team to assist in determining their eligibility.

What if I have questions about the results?

If a genetic mutation is found in your test results, Strand will provide expert counseling and collaborate with your healthcare provider to create a comprehensive health action plan. If you don't have a provider, we'll assist in finding one, ensuring you have a clear plan with actionable steps and resources to empower you on your healthcare journey.

FAQs

How do I order a test?

Tests can be ordered through the Provider Portal or by completing a paper Test Requisition Form.

How long does it take to receive the results?

It typically takes 3-4 weeks from the time a sample is mailed in to receiving the results in our secure provider portal. This timeframe reflects the complexity and precision of our process, as we partner with leading institution labs that adhere to clinical-grade quality control standards. We ensure that every step, from sample analysis to data interpretation, meets the highest level of accuracy and reliability.

Where do I access the results?

Healthcare providers can access their patients' results through the Provider Portal. In some instances, Strand offers direct integration with your EMR system. Contact us today to see if your EMR is supported for integration.

Is this test covered by insurance?

Proactive genetic screening is not covered by insurance, but it is typically eligible for HSA/FSA reimbursement. If you believe your patient may qualify for a diagnostic genetic test, please contact the Strand support team to assist in determining their eligibility.

What if I have questions about the results?

If a genetic mutation is found in your test results, Strand will provide expert counseling and collaborate with your healthcare provider to create a comprehensive health action plan. If you don't have a provider, we'll assist in finding one, ensuring you have a clear plan with actionable steps and resources to empower you on your healthcare journey.

frequently asked questions

How do I order a test?

Tests can be ordered through the Provider Portal or by completing a paper Test Requisition Form.

How long does it take to receive the results?

It typically takes 3-4 weeks from the time a sample is mailed in to receiving the results in our secure provider portal. This timeframe reflects the complexity and precision of our process, as we partner with leading institution labs that adhere to clinical-grade quality control standards. We ensure that every step, from sample analysis to data interpretation, meets the highest level of accuracy and reliability.

Where do I access the results?

Healthcare providers can access their patients' results through the Provider Portal. In some instances, Strand offers direct integration with your EMR system. Contact us today to see if your EMR is supported for integration.

Is this test covered by insurance?

Proactive genetic screening is not covered by insurance, but it is typically eligible for HSA/FSA reimbursement. If you believe your patient may qualify for a diagnostic genetic test, please contact the Strand support team to assist in determining their eligibility.

What if I have questions about the results?

If a genetic mutation is found in your test results, Strand will provide expert counseling and collaborate with your healthcare provider to create a comprehensive health action plan. If you don't have a provider, we'll assist in finding one, ensuring you have a clear plan with actionable steps and resources to empower you on your healthcare journey.

Laboratory / Test Information

Strand’s sequencing is conducted at a leading US-based precision medicine laboratory, certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and accredited by the College of American Pathologists (CAP). We ensure that all data remains within the United States, safeguarded by stringent privacy and security protocols that fully comply with HIPAA regulations to protect your personal health information.

References

  1. Spear BB, Heath-Chiozzi M, Hu J. Clinical application of pharmacogenetics. Trends Mol. Med. 2001; 7, 201–204.

  1. Van Driest SL, Shi Y, Bowton EA, et al. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. American Society for Clinical Pharmacology & Therapeutics https://doi.org/10.1038/clpt.2013.229

  1. Adverse Drug Events in Adults. Centers for Disease Control and Prevention website.: https://www.cdc.gov/medication-safety/data-research/facts-stats/index.html

2024 Strand Bio, Inc. All rights reserved.

2024 Strand Bio, Inc. All rights reserved.

2024 Strand Bio, Inc. All rights reserved.

2024 Strand Bio, Inc. All rights reserved.